SCHEMBL7786206

SCHEMBL7786206

COCC(C)O[Si](OC(C)COC)(OC(C)COC)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
MCHR1 Q99705 1/20 0.36
DHFR P00374 2/20 0.34
DCPS Q96C86 2/20 0.34
LMNA P02545 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HCAR3 P49019 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 3/20 0.31
HTT P42858 1/20 0.31
MAOA P21397 1/20 0.31
PTGS1 P23219 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.31
CA2 P00918 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MPO P05164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL645558 0.80 ALDH1A1 (0.35) MAPTMCHR1LMNAKDM4ETSHR
SCHEMBL106923 0.74 TDP1 (0.37) LMNATSHRALDH1A1MAOATDP1
SCHEMBL19412148 0.74 LMNA (0.47) MAPTLMNAKDM4EMEN1KMT2A
SCHEMBL11130173 0.74 TDP1 (0.33) KDM4EALDH1A1TDP1
SCHEMBL393947 0.74 TDP1 (0.33) KDM4EALDH1A1TDP1
SCHEMBL10710933 0.73 MCHR1 (0.33) MCHR1TSHRALDH1A1
SCHEMBL27841105 0.72 MMP13 (0.33)
SCHEMBL11526330 0.69 ADRA2A (0.40) LMNAKDM4EALDH1A1TDP1
SCHEMBL7065457 0.69 MAPT (0.39) MAPTLMNAKDM4ETSHRALDH1A1
SCHEMBL393946 0.69 CA2 (0.41) LMNAMEN1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789053-B1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 2001-10-24 EP disclosed
US-5852138-A Stabilizer mixtures and their use in polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1998-12-22 US disclosed
EP-0789053-A1 Stabiliser mixtures and their application in polycarbonates BAYER AG (DE) 1997-08-13 EP disclosed