Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767760 | 0.81 | DGAT1 (0.35) | DGAT1PDE10A | |
| SCHEMBL6906012 | 0.79 | P4HB (0.40) | DGAT1MAPT | |
| SCHEMBL6906011 | 0.79 | P4HB (0.40) | DGAT1MAPT | |
| SCHEMBL19810012 | 0.79 | TBXAS1 (0.39) | TBXAS1 | |
| SCHEMBL19810013 | 0.79 | TBXAS1 (0.39) | TBXAS1 | |
| SCHEMBL7500213 | 0.79 | PTPN1 (0.38) | NPC1MAPT | |
| SCHEMBL7499463 | 0.78 | MAPT (0.37) | NPC1MAPT | |
| SCHEMBL16203617 | 0.77 | ACHE (0.35) | DGAT1 | |
| SCHEMBL3973414 | 0.77 | SMN1; SMN2 (0.35) | DGAT1KLKB1NPC1MAPT | |
| SCHEMBL15758042 | 0.76 | SMN1; SMN2 (0.39) | TBXAS1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |