Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906011 | 1.00 | P4HB (0.40) | P4HBMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6905906 | 0.80 | LMNA (0.32) | ALDH1A1LMNADGAT1 | |
| SCHEMBL6905912 | 0.80 | LMNA (0.32) | ALDH1A1LMNADGAT1 | |
| SCHEMBL3939670 | 0.79 | TBXAS1 (0.34) | MAPTDGAT1 | |
| SCHEMBL7500213 | 0.79 | PTPN1 (0.38) | P4HBMAPTGAAKEAP1NFE2L2 | |
| SCHEMBL6905827 | 0.76 | GAA (0.41) | MAPTALDH1A1GAADGAT1MYC | |
| SCHEMBL7499463 | 0.74 | MAPT (0.37) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5098905 | 0.73 | P4HB (0.47) | P4HBMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1767760 | 0.71 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL3070906 | 0.70 | DGAT1 (0.36) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110764-A1 | Inhibitors of prenyl-protein transferase | STUMP CRAIG A (US) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110764-A1 | Inhibitors of prenyl-protein transferase | FNTA, KRAS, PTAR1 | P4HB 1536/4885MAPT 2884/4885ALDH1A1 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.