Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22293254 | 0.74 | G6PC1 (0.39) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL8808223 | 0.73 | SMN1; SMN2 (0.58) | G6PC1HPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9057644 | 0.72 | G6PC1 (0.42) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL9057974 | 0.72 | G6PC1 (0.42) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL4476467 | 0.72 | G6PC1 (0.54) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL10891206 | 0.72 | G6PC1 (0.50) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL9057640 | 0.72 | CYP2C19 (0.53) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL6658628 | 0.71 | AGER (0.41) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL9063369 | 0.71 | G6PC1 (0.43) | G6PC1USP2HPGDHSD17B10SLC6A2 | |
| SCHEMBL9057107 | 0.70 | G6PC1 (0.40) | G6PC1USP2HPGDHSD17B10SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |