Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.37 |
| ▸ | MMP3 | P08254 | 9/20 | 0.37 |
| ▸ | MMP9 | P14780 | 9/20 | 0.37 |
| ▸ | MMP7 | P09237 | 6/20 | 0.37 |
| ▸ | MMP13 | P45452 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 9/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | MMP15 | P51511 | 2/20 | 0.36 |
| ▸ | MMP16 | P51512 | 2/20 | 0.36 |
| ▸ | MMP26 | Q9NRE1 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941142 | 1.00 | MMP1 (0.37) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL3942427 | 0.92 | MMP1 (0.37) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL3942432 | 0.92 | MMP1 (0.37) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL3933301 | 0.87 | MMP1 (0.38) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL3933307 | 0.87 | MMP1 (0.38) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL3942310 | 0.86 | FKBP1A (0.38) | MMP1MAPTMMP2FKBP1AALDH1A1 | |
| SCHEMBL3942316 | 0.86 | FKBP1A (0.38) | MMP1MAPTMMP2FKBP1AALDH1A1 | |
| SCHEMBL3933140 | 0.75 | FKBP1A (0.46) | MMP1MAPTLMNAFKBP1AUSP2 | |
| SCHEMBL4162834 | 0.75 | FKBP1A (0.46) | MMP1MAPTLMNAFKBP1AUSP2 | |
| SCHEMBL3940677 | 0.75 | FKBP1A (0.45) | MMP1MMP3MMP9MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306062-A1 | 2,5-Disubstituted Piperidines | NOVARTIS AG (CH) | 2009-12-10 | — | — | US | disclosed |
| WO-2009106599-A2 | SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |
| EP-2044059-A1 | 2,5-DISUBSTITUTED PIPERIDINES | Speedel Experimenta AG (CH) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007141318-A1 | 2,5-DISUBSTITUTED PIPERIDINES | SPEEDEL EXPERIMENTA AG (CH) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306062-A1 | 2,5-Disubstituted Piperidines | REN, AGTR1, AGTR2 | MMP1 918/4885MMP3 1353/4885MMP9 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.