SCHEMBL3941676

SCHEMBL3941676

COCCCC[C@H](c1cccc(F)c1N1CCCCC1)[C@H]1CCCNC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
REN P00797 7/20 0.33
SLC6A2 P23975 3/20 0.31
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5593564 0.85 SLC6A2 (0.34) RENSLC6A2SLC6A4SLC6A3HTR1A
SCHEMBL5613173 0.80 SLC6A2 (0.36) RENSLC6A2SLC6A4SLC6A3
SCHEMBL4755799 0.79 REN (0.41) RENSLC6A2SLC6A4SLC6A3
SCHEMBL4754589 0.79 REN (0.41) RENSLC6A2SLC6A4SLC6A3
SCHEMBL5593634 0.77 SLC6A2 (0.41) RENSLC6A2SLC6A4SLC6A3
SCHEMBL5612896 0.76 REN (0.33) RENSLC6A2SLC6A4SLC6A3
SCHEMBL5612488 0.75 SLC6A2 (0.33) RENSLC6A2SLC6A4SLC6A3
SCHEMBL5593301 0.75 SLC6A2 (0.35) RENSLC6A2SLC6A4
SCHEMBL3879197 0.73 SLC6A2 (0.38) RENSLC6A2SLC6A4SLC6A3
SCHEMBL3949544 0.73 REN (0.45) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118373858-A Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-07-23 CN claimed
CN-117443456-B Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-04-05 CN claimed
CN-117443456-A Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-01-26 CN claimed
CN-118022720-B Integrated desulfurization catalyst, preparation method and application 中国石油化工股份有限公司 2026-05-19 CN disclosed
CN-118416967-A Rhodium catalyst separation and recovery method and application thereof 中国石油化工股份有限公司 2024-08-02 CN disclosed
CN-118373858-A Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-07-23 CN disclosed
CN-118022720-A Integrated desulfurization catalyst, preparation method and application 中国石油化工股份有限公司 2024-05-14 CN disclosed
CN-117443456-B Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-04-05 CN disclosed
CN-117463304-B Polymer adsorbent and method for recovering rhodium in rhodium-containing waste liquid based on same 北京高新利华科技股份有限公司 2024-04-05 CN disclosed
CN-117463304-A Polymer adsorbent and method for recovering rhodium in rhodium-containing waste liquid based on same 北京高新利华科技股份有限公司 2024-01-30 CN disclosed
CN-117443456-A Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-01-26 CN disclosed
WO-2007117559-A2 RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-10-18 WO disclosed
US-7195889-B2 Process for stabilizing enzymes with phosphine or phosphite compounds EASTMAN CHEMICAL COMPANY (US) 2007-03-27 US disclosed
EP-1621613-A1 Enzymatic reductions with dihydrogen via metal catalyzed cofactor regeneration EASTMAN CHEMICAL COMPANY (US) 2006-02-01 EP disclosed
US-6599723-B1 Redox system for use in the generation of reduced organic product; obtain reaction mixture, incubate with nicotinamide cofactor, recover reduced organic product EASTMAN CHEMICAL COMPANY 2003-07-29 US disclosed
US-20030124696-A1 Process for stabilizing the activity of enzymes with phosphorus compounds EASTMAN CHEMICAL COMPANY 2003-07-03 US disclosed
CN-1403604-A Method of recovering metal rhodium from waste olefine carbonylating catalyst liquid CHINA PETROCHEMICAL CORP (CN) 2003-03-19 CN disclosed
EP-1181356-A2 ENZYMATIC REDUCTIONS WITH DIHYDROGEN VIA METAL CATALYZED COFACTOR REGENERATION EASTMAN CHEMICAL COMPANY (US) 2002-02-27 EP disclosed
WO-2000053731-A2 ENZYMATIC REDUCTIONS WITH DIHYDROGEN VIA METAL CATALYZED COFACTOR REGENERATION EASTMAN CHEMICAL COMPANY (US) 2000-09-14 WO disclosed
US-4397788-A COMPLEXING IN PRESENCE OF BOROHYDRIDE REDUCTING AGENT TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1983-08-09 US disclosed