Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.64 |
| ▸ | NQO2 | P16083 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MASP2 | O00187 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methylbenzimidamide SCHEMBL524027 | 0.93 | LMNA (0.59) | WDR5NQO2ALDH1A1HPGDHSD17B10 | |
| 4-Methylbenzimidamide SCHEMBL28504756 | 0.90 | PRSS1 (0.61) | NQO2ALDH1A1HPGDHSD17B10PRMT1 | |
| 4-Methylbenzimidamide SCHEMBL1019464 | 0.90 | PRSS1 (0.61) | NQO2ALDH1A1HPGDHSD17B10PRMT1 | |
| 4-Methylbenzimidamide SCHEMBL1436204 | 0.88 | LMNA (0.54) | WDR5NQO2ALDH1A1HPGDHSD17B10 | |
| 4-Methylbenzimidamide SCHEMBL28496422 | 0.88 | PRSS1 (0.58) | NQO2ALDH1A1HPGDHSD17B10PRMT1 | |
| SCHEMBL394218 | 0.87 | WDR5 (0.80) | WDR5NQO2ALDH1A1TOP1HPGD | |
| SCHEMBL8973288 | 0.87 | WDR5 (0.80) | WDR5NQO2ALDH1A1TOP1HPGD | |
| 4-Methylbenzimidamide SCHEMBL28399173 | 0.82 | BLM (0.74) | WDR5NQO2PLAULMNAMASP2 | |
| SCHEMBL20364177 | 0.80 | ST14 (0.79) | ALDH1A1TDP1PLAUPRSS1PRSS3 | |
| 4-Methylbenzimidamide SCHEMBL1050355 | 0.80 | NQO2 (0.51) | NQO2ALDH1A1HPGDHSD17B10PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481966-B1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |