Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952000 | 0.89 | SLC16A3 (0.40) | CASRHDAC3HDAC1HDAC2SLC16A3 | |
| SCHEMBL3945243 | 0.85 | FYN (0.39) | HDAC3HDAC1HDAC2HDAC6SLC16A3 | |
| SCHEMBL3946482 | 0.82 | ALOX5 (0.39) | SLC16A3ALOX5MEN1LMNAKMT2A | |
| SCHEMBL3944707 | 0.79 | CCNE2 (0.39) | CASRGAAMAPT | |
| SCHEMBL3947316 | 0.79 | CASR (0.41) | CASRSLC16A3ALOX5MEN1LMNA | |
| SCHEMBL3942439 | 0.78 | ALOX5 (0.38) | OPRK1ALOX5MEN1LMNAKMT2A | |
| SCHEMBL1384031 | 0.76 | CASR (0.53) | CASRHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3948201 | 0.76 | SLC6A2 (0.37) | CASRSLC16A3ALOX5MEN1LMNA | |
| SCHEMBL3951648 | 0.76 | TSPO (0.37) | CASROPRK1ALOX5TP53 | |
| SCHEMBL1386304 | 0.76 | SLC16A3 (0.41) | CASRHDAC3HDAC1HDAC2SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718632-B1 | PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SANOFI AVENTIS (FR) | 2009-04-22 | — | — | EP | claimed |