Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943254 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| Hydrazine SCHEMBL28200090 | 0.96 | ALDH1A1 (0.53) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL4305407 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL2501666 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL2333531 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL31443947 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL4102754 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL27494789 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL8321794 | 0.80 | CTSB (0.53) | ALDH1A1TDP1NPC1RAB9AHPGD | |
| SCHEMBL8321796 | 0.80 | CTSB (0.53) | ALDH1A1TDP1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182452-A1 | METHODS FOR SYNTHESIZING NON-ANTICOAGULANT HEPARAN SULFATE | Optimvia, LLC (US) | 2023-05-24 | — | — | EP | claimed |
| EP-3997238-A1 | METHODS FOR SYNTHESIZING ANTICOAGULANT POLYSACCHARIDES | Optimvia, LLC (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3911737-A1 | ENGINEERED ARYL SULFATE-DEPENDENT ENZYMES | Optimvia, LLC (US) | 2021-11-24 | — | — | EP | claimed |
| WO-2021007429-A1 | METHODS FOR SYNTHESIZING ANTICOAGULANT POLYSACCHARIDES | OPTIMVIA LLC (US) | 2021-01-14 | — | — | WO | claimed |
| WO-2020150350-A1 | ENGINEERED ARYL SULFATE-DEPENDENT ENZYMES | OPTIMVIA, LLC (US) | 2020-07-23 | — | — | WO | claimed |
| WO-2018175464-A1 | ENZYMATIC PREPARATION OF INCREASED ANTICOAGULANT BOVINE SOURCED HEPARIN | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2018-09-27 | — | — | WO | claimed |
| EP-2761017-A1 | SYSTEMS AND METHODS FOR PREDICTING RESPONSE TO MINOXIDIL FOR THE TREATMENT OF ANDROGENETIC ALOPECIA | Follea International Limited (CN) | 2014-08-06 | — | — | EP | claimed |
| WO-2013049258-A1 | SYSTEMS AND METHODS FOR PREDICTING RESPONSE TO MINOXIDIL FOR THE TREATMENT OF ANDROGENETIC ALOPECIA | FOLLEA INTERNATIONAL (US) | 2013-04-04 | — | — | WO | claimed |
| WO-2009014715-A2 | ENZYMATIC SYNTHESIS OF SULFATED POLYSACCHARIDES WITHOUT IDURONIC ACID RESIDUES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-01-29 | — | — | WO | claimed |
| EP-1885865-A2 | ENZYMATIC SYNTHESIS OF SULFATED POLYSACCHARIDES | The University of North Carolina at Chapel Hill (US) | 2008-02-13 | — | — | EP | claimed |
| WO-2006124801-A2 | ENZYMATIC SYNTHESIS OF SULFATED POLYSACCHARIDES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-11-23 | — | — | WO | claimed |
| EP-0531537-A1 | HIRUDIN ANALOGUE OR SALT THEREOF, PRODUCTION THEREOF, AND ANTICOAGULANT CONTAINING THE SAME AS ACTIVE INGREDIENT | JAPAN ENERGY CORPORATION (JP) | 1993-03-17 | — | — | EP | claimed |
| CN-118078847-A | Alopecia preventing composition and preparation method and application thereof | 开远市洁白洗涤用品有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-11939303-B2 | Sulfamate derivatives of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol, derivatives of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol, their medical use and the method of obtaining 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamate derivatives | POLITECHNIKA GDANSKA (PL) | 2024-03-26 | — | — | US | disclosed |
| US-20240076634-A1 | ENGINEERED ARYL SULFATE-DEPENDENT ENZYMES | GINKGO BIOWORKS, INC. | 2024-03-07 | — | — | US | disclosed |
| WO-2023239972-A1 | MINOXIDIL ADJUVANT THERAPIES | Jupiter Wellness, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2000001691-A1 | PROCESS FOR MAKING FARNESYL-PROTEIN TRANSFERASE INHIBITORS | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | disclosed |
| WO-2000001674-A1 | PROCESS FOR MAKING 1,5-DISUBSTITUTED IMIDAZOLES | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | disclosed |
| WO-1998003636-A9 | NOVEL ARYLSULFOTRANSFERASE | — | 1998-05-22 | — | — | WO | disclosed |
| WO-1998003636-A1 | NOVEL ARYLSULFOTRANSFERASE | BIO-TECHNICAL RESOURCES (US) | 1998-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939303-B2 | Sulfamate derivatives of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol, derivatives of 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenol, their medical use and the method of obtaining 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamate derivatives | SULT1E1, SULT2A1, SULT1A1 | ALDH1A1 507/4885TDP1 2518/4885NPC1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.