Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAP2 | P11137 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951020 | 0.95 | FAAH (0.50) | LHCGRFAAHMAPK10ALDH1A1RAB9A | |
| SCHEMBL3945148 | 0.83 | MAPT (0.56) | LHCGRALDH1A1GSK3BKDM4EMAPT | |
| SCHEMBL3947601 | 0.83 | BRD4 (0.42) | ALDH1A1GSK3BADKKDM4EGAA | |
| SCHEMBL4930105 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAMAPTMAP2 | |
| SCHEMBL3951863 | 0.79 | ALDH1A1 (0.43) | FAAHALDH1A1GSK3BADKKDM4E | |
| SCHEMBL3945036 | 0.79 | MAPT (0.53) | LHCGRFAAHMAPK10ALDH1A1RAB9A | |
| SCHEMBL3946744 | 0.78 | LIPE (0.41) | ALDH1A1GSK3BADKKDM4EGAA | |
| SCHEMBL3942136 | 0.78 | NPC1 (0.39) | ALDH1A1RAB9AGSK3BADKKDM4E | |
| SCHEMBL3951513 | 0.77 | HTR2C (0.39) | FAAHALDH1A1GSK3BADKKDM4E | |
| SCHEMBL5187596 | 0.76 | NPC1 (0.41) | ALDH1A1RAB9AKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802572-B1 | INDOL DERIVATIVES AS INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-04-22 | — | — | EP | disclosed |
| EP-1802572-A1 | INDOL DERIVATIVES AS INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006032541-A1 | INDOL DERIVATIVES AS INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-03-30 | — | — | WO | disclosed |