Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92970 | 0.89 | LOXL2 (0.58) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 | |
| Hydrogen Sulfide SCHEMBL27473257 | 0.87 | LOXL2 (0.56) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL27707919 | 0.87 | LOXL2 (0.56) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL12807987 | 0.83 | MMP3 (0.58) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL31591073 | 0.83 | SAE1 (0.56) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL3236728 | 0.83 | MMP3 (0.58) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 | |
| Phosphoric Acid SCHEMBL28852152 | 0.79 | LOXL2 (0.48) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL3178059 | 0.78 | MAOB (0.59) | LOXL2CYP2A6CYP11B1CYP11B2IDO1 | |
| SCHEMBL3233441 | 0.78 | LTA4H (0.59) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL17253336 | 0.78 | CYP1B1 (0.47) | LOXL2CYP2A6CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896492-B1 | PLATINUM COMPLEXES WITH MONONITRILE-CONTAINING LIGANDS | BIONUMERIK PHARMACEUTICALS INC (US) | 2014-03-19 | — | — | EP | claimed |
| EP-1896492-B1 | PLATINUM COMPLEXES WITH MONONITRILE-CONTAINING LIGANDS | BIONUMERIK PHARMACEUTICALS INC (US) | 2014-03-19 | — | — | EP | disclosed |
| US-7569606-B2 | Platinum complexes with mononitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-20070173485-A1 | Amminecyclohexanecarbonitriledichloroplatinum; platinum is capable of rapidly undergoing chelation with the Guanine or Adenine base of a DNA oligonucleotide at the 7 position; readily taken up by tumor cells | JUNIPER NETWORKS, INC. | 2007-07-26 | — | — | US | disclosed |
| US-7238823-B2 | Platinum complexes with mononitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-20070004798-A1 | Platinum complexes with mononitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004798-A1 | Platinum complexes with mononitrile-containing ligands | LIG4, RNMT, LIG1 | LOXL2 3787/4885CYP2A6 3192/4885CYP11B1 3517/4885 |
| US-20070173485-A1 | Amminecyclohexanecarbonitriledichloroplatinum; platinum is capable of rapidly undergoing chelation with the Guanine or Adenine base of a DNA oligonucleotide at the 7 position; readily taken up by tumor cells | RNMT, NSUN2, NUDT1 | LOXL2 3229/4885CYP2A6 3216/4885CYP11B1 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.