SCHEMBL3945323

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3951281	1.00	BRD4 (0.52)	BRD4SERPINE1BACE1CA1CA2
	SCHEMBL3953578	0.99	BRD4 (0.52)	BRD4SERPINE1BACE1CA1CA2
	SCHEMBL3946743	0.96	BRD4 (0.54)	BRD4SERPINE1CA1CA2CA12
	SCHEMBL3952168	0.93	BRD4 (0.51)	BRD4SERPINE1CA1CA2CA12
	SCHEMBL3952273	0.93	RAB9A (0.51)	BRD4SERPINE1CA1CA2CA12
	SCHEMBL3946013	0.92	BRD4 (0.50)	BRD4SERPINE1CA1CA2CA12
	SCHEMBL3944080	0.91	HTR6 (0.50)	BRD4SERPINE1CA1CA2CA12
	SCHEMBL3952118	0.88	BRD4 (0.49)	BRD4SERPINE1CA1CA2CA12
	SCHEMBL3944581	0.88	SERPINE1 (0.54)	BRD4SERPINE1MEN1ALDH1A1KMT2A
	SCHEMBL3945072	0.87	TGFBR1 (0.49)	BRD4SERPINE1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.