Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943937 | 0.87 | NPY5R (0.47) | NPY5RRAB9AGAAATM | |
| SCHEMBL4112185 | 0.84 | NPY5R (0.44) | NPY5RHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3945243 | 0.80 | FYN (0.39) | HDAC3HDAC1HDAC2HDAC6F2 | |
| SCHEMBL3951253 | 0.76 | NPY5R (0.46) | NPY5RGAA | |
| SCHEMBL1383227 | 0.76 | ALDH1A1 (0.42) | HDAC3HDAC1HDAC2HDAC6F2 | |
| SCHEMBL3442903 | 0.72 | KDM4C (0.53) | HDAC3HDAC1HDAC2HDAC6F2 | |
| SCHEMBL3443587 | 0.70 | ALDH1A1 (0.58) | HDAC3HDAC1HDAC2HDAC6F2 | |
| SCHEMBL1384100 | 0.70 | FYN (0.39) | HDAC3HDAC1HDAC2HDAC6F2 | |
| SCHEMBL3952000 | 0.67 | SLC16A3 (0.40) | HDAC3HDAC1HDAC2RAB9ALMNA | |
| SCHEMBL3946609 | 0.66 | NPY5R (0.43) | NPY5RGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718632-B1 | PYRIMIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SANOFI AVENTIS (FR) | 2009-04-22 | — | — | EP | claimed |