Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13800677 | 0.87 | RAPGEF4 (0.51) | RAPGEF4TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL13800740 | 0.86 | SLC2A1 (0.41) | PTGS2DRD1CYP3A4TDP1MEN1 | |
| SCHEMBL2044796 | 0.81 | TDP1 (0.50) | PTGS2DRD1CYP3A4TDP1MEN1 | |
| SCHEMBL3952888 | 0.79 | LMNA (0.40) | DRD1CYP3A4TDP1KMT2ALMNA | |
| SCHEMBL1921293 | 0.77 | RAPGEF4 (0.57) | PTGS2RAPGEF4MEN1KMT2AALDH1A1 | |
| SCHEMBL4136434 | 0.76 | PTGS2 (0.43) | PTGS2RAPGEF4MEN1KMT2AALDH1A1 | |
| SCHEMBL29053285 | 0.76 | MAPT (0.48) | PTGS2DRD1CYP3A4TDP1MEN1 | |
| SCHEMBL30842833 | 0.76 | MAPT (0.48) | PTGS2DRD1CYP3A4TDP1MEN1 | |
| SCHEMBL49858 | 0.75 | CYP3A4 (0.52) | DRD1CYP3A4TDP1ALDH1A1LMNA | |
| SCHEMBL4800221 | 0.75 | RAPGEF4 (0.55) | PTGS2RAPGEF4TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265488-B | Iridium anticancer complex containing phosphinimine bidentate chelating ligand and preparation method and application thereof | 曲阜师范大学 | 2021-03-02 | — | — | CN | claimed |
| US-7553924-B2 | Catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY (RW) | 2009-06-30 | — | — | US | claimed |
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NATIONAL SUN YAT-SEN UNIVERSITY | 2009-06-25 | — | — | US | claimed |
| US-7271276-B2 | Metal complexes for catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2007-09-18 | — | — | US | claimed |
| US-20050288505-A1 | Metal complexes for catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-12-29 | — | — | US | claimed |
| US-20050288504-A1 | Ligands for metals as catalysts for carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-12-29 | — | — | US | claimed |
| US-20050137382-A1 | Catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-06-23 | — | — | US | claimed |
| CN-109265488-B | Iridium anticancer complex containing phosphinimine bidentate chelating ligand and preparation method and application thereof | 曲阜师范大学 | 2021-03-02 | — | — | CN | disclosed |
| US-7553924-B2 | Catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY (RW) | 2009-06-30 | — | — | US | disclosed |
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NATIONAL SUN YAT-SEN UNIVERSITY | 2009-06-25 | — | — | US | disclosed |
| US-7271276-B2 | Metal complexes for catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2007-09-18 | — | — | US | disclosed |
| US-20050288505-A1 | Metal complexes for catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-12-29 | — | — | US | disclosed |
| US-20050288504-A1 | Ligands for metals as catalysts for carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-12-29 | — | — | US | disclosed |
| US-20050137382-A1 | Catalytic carbon-carbon bond formation | NATIONAL SUN YAT-SEN UNIVERSITY | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NCOR2, OXGR1, NCOR1 | PTGS2 718/4885RAPGEF4 3059/4885DRD1 216/4885 |
| US-20050137382-A1 | Catalytic carbon-carbon bond formation | CBR1, NR1H2, NR1H3 | PTGS2 675/4885RAPGEF4 3549/4885DRD1 319/4885 |
| US-20050288504-A1 | Ligands for metals as catalysts for carbon-carbon bond formation | NCOR2, NCOR1, NR1I2 | PTGS2 763/4885RAPGEF4 2877/4885DRD1 321/4885 |
| US-20050288505-A1 | Metal complexes for catalytic carbon-carbon bond formation | CBR1, NR2C2, NCOR2 | PTGS2 778/4885RAPGEF4 3268/4885DRD1 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.