Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 7/20 | 0.42 |
| ▸ | PYGM | P11217 | 5/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314932 | 0.84 | PYGL (0.43) | PYGLPYGMCRBNDDB1RIPK1 | |
| SCHEMBL25330404 | 0.83 | PYGL (0.42) | PYGLPYGMCRBNDDB1RIPK1 | |
| SCHEMBL27766819 | 0.82 | EPHX2 (0.46) | PYGLPYGMCRBNBRD4 | |
| SCHEMBL2840737 | 0.78 | PYGL (0.42) | PYGLPYGMCRBNDDB1KDM4E | |
| SCHEMBL29900499 | 0.77 | PYGL (0.64) | PYGLPYGMRIPK1BRD4 | |
| SCHEMBL15541576 | 0.77 | PYGL (0.64) | PYGLPYGMRIPK1BRD4 | |
| SCHEMBL25329367 | 0.77 | PYGL (0.64) | PYGLPYGMRIPK1BRD4 | |
| SCHEMBL1450613 | 0.76 | PARP1 (0.36) | CRBNDDB1KDM4EALDH1A1IKZF3 | |
| SCHEMBL5311229 | 0.75 | RIPK1 (0.45) | PYGLPYGMCRBNDDB1RIPK1 | |
| SCHEMBL4390484 | 0.74 | PYGL (0.46) | PYGLPYGMCRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | PYGL 3956/4885PYGM 4649/4885CRBN 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.