SCHEMBL394849

SCHEMBL394849

C=C(Cc1ccc(S(=O)(=O)N(CC)CC)cc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
HTT P42858 4/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
RAB9A P51151 3/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 3/20 0.48
TAS2R14 Q9NYV8 2/20 0.47
HPGD P15428 1/20 0.45
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
ABCC2 Q92887 1/20 0.44
SLC22A12 Q96S37 1/20 0.44
UGT1A7 Q9HAW7 1/20 0.44
SLC22A11 Q9NSA0 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397779 0.84 ALDH1A1 (0.49) LMNAHTTSMN1; SMN2ALDH1A1MEN1
SCHEMBL5452529 0.84 LMNA (0.59) LMNAHTTSMN1; SMN2RAB9ANPC1
SCHEMBL394852 0.83 POLB (0.54) LMNAHTTSMN1; SMN2RAB9AALDH1A1
SCHEMBL8490338 0.79 AKR1C3 (0.46)
SCHEMBL3426193 0.76 CA2 (0.46) LMNAHTTALDH1A1HPGDCA2
SCHEMBL396597 0.76 ALDH1A1 (0.60) LMNASMN1; SMN2RAB9ANPC1ALDH1A1
SCHEMBL396733 0.76 CA2 (0.54) SMN1; SMN2CA12CA2CA9KMT2A
SCHEMBL395695 0.75 SMN1; SMN2 (0.46) LMNAHTTSMN1; SMN2RAB9ANPC1
SCHEMBL6442701 0.75 ALDH1A1 (0.52) LMNASMN1; SMN2ALDH1A1HPGDCA2
SCHEMBL5024746 0.75 LMNA (0.70) LMNAHTTSMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed