SCHEMBL394852

SCHEMBL394852

C=C(Cc1cccc(S(=O)(=O)N(CC)CC)c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
ALDH1A1 P00352 7/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
TSHR P16473 3/20 0.54
LMNA P02545 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
APEX1 P27695 1/20 0.46
MAPT P10636 4/20 0.44
MAPK1 P28482 2/20 0.44
KDM4E B2RXH2 2/20 0.44
HSP90AA1 P07900 1/20 0.44
RAB9A P51151 1/20 0.44
GAA P10253 1/20 0.44
XBP1 P17861 1/20 0.44
HTT P42858 1/20 0.44
PAX8 Q06710 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396070 0.86 RAB9A (0.56) ALDH1A1SMN1; SMN2TSHRLMNAMEN1
SCHEMBL394849 0.83 LMNA (0.53) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL397249 0.79 CA1 (0.48) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL392888 0.78 ALDH1A1 (0.45) ALDH1A1LMNAKMT2AHTT
SCHEMBL398496 0.78 POLB (0.44) POLBSMN1; SMN2LMNAMAPK1HTT
SCHEMBL14376200 0.78 ALDH1A1 (0.69) POLBALDH1A1SMN1; SMN2TSHRLMNA
SCHEMBL397724 0.76 AKR1C3 (0.48) ALDH1A1KMT2AHTTNPSR1
SCHEMBL3423556 0.75 CTBP2 (0.44)
SCHEMBL398535 0.75 KDM4E (0.52) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL397008 0.74 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2TSHRLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed