Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426193 | 0.89 | CA2 (0.46) | ALDH1A1HPGDHSD17B10LMNACTBP2 | |
| SCHEMBL1921797 | 0.83 | CTBP2 (0.56) | ALDH1A1SMN1; SMN2HPGDTDP1LMNA | |
| SCHEMBL2732935 | 0.83 | LMNA (0.54) | ALDH1A1HPGDLMNARXRARXRB | |
| SCHEMBL83884 | 0.81 | CA2 (0.61) | LMNACTBP2CA2CAMK2A | |
| SCHEMBL41907 | 0.80 | CES1 (0.58) | ALDH1A1LMNAMEN1KMT2ACTBP2 | |
| SCHEMBL15301307 | 0.80 | ALDH1A1 (0.48) | ALDH1A1PLK1HPGDHSD17B10TDP1 | |
| SCHEMBL9223252 | 0.80 | LOXL2 (0.56) | TDP1MEN1KMT2ACA2MAPT | |
| SCHEMBL8861677 | 0.80 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2KDM4EHPGDTDP1 | |
| SCHEMBL397389 | 0.79 | MEN1 (0.49) | ALDH1A1SMN1; SMN2HPGDLMNAMEN1 | |
| SCHEMBL1629363 | 0.79 | CTBP2 (0.56) | ALDH1A1HPGDTDP1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015505-B1 | PRODUCTION OF PHOTOPOLYMERIZED POLYESTER HIGH INDEX OPHTHALMIC LENSES | SIGNET ARMORLITE INC (US) | 2005-03-09 | — | — | EP | claimed |
| EP-0783710-B1 | POLYESTER RESIN-BASED HIGH INDEX OPHTHALMIC LENSES HAVING IMPROVED OPTICAL UNIFORMITY AND/OR TINTABILITY | SIGNET ARMORLITE INC (US) | 2002-05-29 | — | — | EP | claimed |