Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409711 | 0.86 | GABRA5 (0.43) | ITGB3ITGA2BHRH3SLC6A1GABRA5 | |
| SCHEMBL4578412 | 0.84 | — | — | |
| SCHEMBL8741893 | 0.83 | ITGB3 (0.36) | ITGB3ITGA2BHRH3SLC6A1GABRA5 | |
| SCHEMBL7357879 | 0.82 | SLC6A1 (0.46) | ITGB3ITGA2BHRH3HIF1ASLC6A1 | |
| SCHEMBL2076622 | 0.79 | CYP1A2 (0.46) | HIF1ATSHR | |
| SCHEMBL8944666 | 0.79 | — | — | |
| SCHEMBL13673452 | 0.78 | HRH3 (0.39) | ITGB3ITGA2BHRH3FAAHGNAO1 | |
| SCHEMBL237382 | 0.78 | ITGB3 (0.47) | ITGB3ITGA2BHRH3SLC6A1GABRA5 | |
| SCHEMBL331124 | 0.78 | HRH3 (0.47) | ITGB3ITGA2BHRH3SLC6A1GABRA5 | |
| SCHEMBL3956314 | 0.78 | GNAI3 (0.42) | ITGB3ITGA2BHRH3SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |
| EP-0693067-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-01-12 | — | — | EP | disclosed |
| EP-0664792-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-01-05 | — | — | EP | disclosed |
| EP-0478362-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1999-06-09 | — | — | EP | disclosed |
| EP-0512829-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5721253-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| EP-0664792-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5272158-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1993-12-21 | — | — | US | disclosed |
| US-5264420-A | Anticoagulants | MERCK & CO., INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0540334-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| EP-0512829-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| CN-1060293-A | Fibrinogen receptor anlagonists | MERCK & CO INC (US) | 1992-04-15 | — | — | CN | disclosed |
| EP-0479481-A2 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| CN-1060096-A | FIBRINOGEN RECEPTOR ANLAGONISTS | MERCK & CO INC (US) | 1992-04-08 | — | — | CN | disclosed |
| EP-0478362-A2 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| CN-1046529-A | Carbostyril derivative | OTSUKA PHARMA CO LTD (JP) | 1990-10-31 | — | — | CN | disclosed |