SCHEMBL3948654

SCHEMBL3948654

C=C(c1cccc(C(=C)[Si](C)(C)Cl)c1)[Si](C)(C)Cl

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FURIN P09958 1/20 0.32
ACHE P22303 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
CREBBP Q92793 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3949050 0.81 ATM (0.36) TDP1ATML3MBTL1FURIN
SCHEMBL3956054 0.80 MAPT (0.32) HSD17B10
SCHEMBL3951762 0.74 CES2 (0.34) TDP1ATML3MBTL1FURINACHE
SCHEMBL3950490 0.71 MAOA (0.34)
SCHEMBL4135724 0.71 CES2 (0.35) TDP1ATML3MBTL1FURIN
SCHEMBL11654664 0.70 MAOA (0.39) ATM
SCHEMBL23045171 0.69 ATM (0.40) TDP1ATML3MBTL1
SCHEMBL4440082 0.67 TDP1 (0.40) TDP1ATML3MBTL1FURINHDAC8
SCHEMBL167439 0.67 FURIN (0.43) TDP1ATML3MBTL1FURINHDAC8
SCHEMBL3952678 0.67 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556860-B2 Laminate and method of forming the same, insulating film, and semiconductor device JSR CORPORATION (JP) 2009-07-07 US disclosed
US-20060216531-A1 Laminate and method of forming the same, insulating film, and semiconductor device JSR CORPORATION (JP) 2006-09-28 US disclosed
EP-1679184-A1 LAMINATE AND METHOD FOR FORMATION THEREOF, INSULATING FILM, SEMICONDUCTOR DEVICE, AND COMPOSITION FOR FORMING FILM JSR Corporation (JP) 2006-07-12 EP disclosed