SCHEMBL3950490

SCHEMBL3950490

C=C(c1ccccc1C(=C)[Si](C)(C)Cl)[Si](C)(C)Cl

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
ALDH1A1 P00352 2/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3956173 0.79 ALDH1A1 (0.33) MAOAMAOBCES2CES1ALDH1A1
SCHEMBL3956054 0.74 MAPT (0.32) MAOAMAOB
SCHEMBL3955265 0.71 TSHR (0.33) ALDH1A1
SCHEMBL3948654 0.71 TDP1 (0.33)
SCHEMBL3948528 0.68 TSHR (0.34) ALDH1A1
SCHEMBL11654664 0.68 MAOA (0.39) MAOAMAOBCES2CES1ALDH1A1
SCHEMBL5376342 0.67 NPC1 (0.45) ALDH1A1ALOX15
SCHEMBL28726229 0.64 CES1 (0.41) CES2CES1ALDH1A1
SCHEMBL3950687 0.64 TSHR (0.41) MAOAMAOBALDH1A1
SCHEMBL107161 0.64 MEN1 (0.40) MAOAMAOBALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556860-B2 Laminate and method of forming the same, insulating film, and semiconductor device JSR CORPORATION (JP) 2009-07-07 US disclosed
US-20060216531-A1 Laminate and method of forming the same, insulating film, and semiconductor device JSR CORPORATION (JP) 2006-09-28 US disclosed
EP-1679184-A1 LAMINATE AND METHOD FOR FORMATION THEREOF, INSULATING FILM, SEMICONDUCTOR DEVICE, AND COMPOSITION FOR FORMING FILM JSR Corporation (JP) 2006-07-12 EP disclosed