Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.43 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452422 | 0.82 | NR3C1 (0.49) | NR3C2NR3C1PGRCYP3A4 | |
| SCHEMBL3658512 | 0.81 | CYP2C19 (0.41) | NR3C2NR1H2NR1H3ALDH1A1TSHR | |
| SCHEMBL4430210 | 0.78 | PDK1 (0.43) | TAAR1NR3C2NR1H2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3684124 | 0.77 | CYP19A1 (0.36) | NR3C2NR3C1PGRNR1H2NR1H3 | |
| SCHEMBL3653019 | 0.76 | NR3C1 (0.35) | NR3C2NR3C1PGRNR1H2NR1H3 | |
| SCHEMBL3530975 | 0.76 | NR3C1 (0.51) | TAAR1NR3C2NR3C1PGRSHBG | |
| SCHEMBL3658752 | 0.76 | NR3C1 (0.34) | NR3C2NR3C1PGRNR1H2NR1H3 | |
| SCHEMBL14158802 | 0.76 | L3MBTL1 (0.45) | ALDH1A1CYP3A4PDK2 | |
| SCHEMBL21245467 | 0.76 | TAAR1 (0.54) | TAAR1NR3C2NR3C1PGRSHBG | |
| SCHEMBL28013950 | 0.76 | TAAR1 (0.54) | TAAR1SHBGALDH1A1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061444-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | Bausch & Lomb Incorporated (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-2056799-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING GLAUCOMA OR PROGRESSION THEREOF | Bausch & Lomb Incorporated (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008033655-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | BAUSCH & LOMB INCORPORATED (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008027796-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING GLAUCOMA OR PROGRESSION THEREOF | BAUSCH & LOMB INCORPORATED (US) | 2008-03-06 | — | — | WO | disclosed |