Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 7/20 | 0.39 |
| ▸ | YES1 | P07947 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680443 | 0.86 | THRA (0.44) | PPARDPPARASRCFFAR1FFAR4 | |
| SCHEMBL3882520 | 0.85 | KEAP1 (0.38) | PPARDPPARASRCYES1KEAP1 | |
| SCHEMBL3881996 | 0.85 | KEAP1 (0.40) | PPARDPPARASRCYES1FFAR1 | |
| SCHEMBL3882409 | 0.85 | PTGER1 (0.42) | PPARDPPARASRCYES1FFAR1 | |
| SCHEMBL3890246 | 0.84 | PTGER1 (0.40) | PPARDPPARASRCYES1FFAR1 | |
| SCHEMBL3883892 | 0.83 | SRC (0.40) | SRCYES1KEAP1NFE2L2C5AR1 | |
| SCHEMBL3675705 | 0.83 | MEN1 (0.38) | PPARDPPARASRCFFAR1FFAR4 | |
| SCHEMBL3884083 | 0.82 | RORC (0.39) | SRCYES1KEAP1NFE2L2KDM4E | |
| SCHEMBL3884439 | 0.82 | C5AR1 (0.42) | SRCYES1KEAP1NFE2L2C5AR1 | |
| SCHEMBL3888318 | 0.82 | PTGER1 (0.39) | PPARDPPARASRCYES1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |