Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14206747 | 0.90 | ADRA2C (0.56) | ADRA2CSLC6A7NPC1RAB9AMEN1 | |
| SCHEMBL3529262 | 0.74 | HSD17B10 (0.49) | SLC6A7NPC1RAB9AMEN1SCD | |
| SCHEMBL29102030 | 0.73 | — | — | |
| SCHEMBL3529417 | 0.73 | ALDH1A1 (0.55) | SLC6A7NPC1RAB9AMEN1SCD | |
| SCHEMBL3016546 | 0.71 | RAB9A (0.65) | SLC6A7NPC1RAB9AMEN1SCD | |
| Hydrochloric Acid SCHEMBL27752386 | 0.70 | RAB9A (0.63) | SLC6A7NPC1RAB9AMEN1SCD | |
| SCHEMBL22495221 | 0.69 | NPC1 (0.66) | ADRA2CSLC6A7NPC1RAB9AMEN1 | |
| SCHEMBL3151850 | 0.69 | DRD2 (0.41) | SLC6A7NPC1RAB9AMEN1SCD | |
| SCHEMBL23152040 | 0.68 | ADRA2C (0.79) | ADRA2CMEN1KEAP1DRD2GAA | |
| SCHEMBL11775877 | 0.68 | ADRA2C (0.79) | ADRA2CMEN1KEAP1DRD2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078003-A1 | ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008054702-A1 | ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |