Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529417 | 0.83 | ALDH1A1 (0.55) | HSD17B10SLC6A7RAB9ADRD4DRD3 | |
| SCHEMBL14206747 | 0.83 | ADRA2C (0.56) | HSD17B10SLC6A7DRD2RAB9ADRD4 | |
| SCHEMBL29102030 | 0.80 | — | — | |
| SCHEMBL3016546 | 0.78 | RAB9A (0.65) | HSD17B10SLC6A7DRD2RAB9ADRD4 | |
| SCHEMBL14206746 | 0.77 | HTT (0.52) | HSD17B10SLC6A7RAB9ADRD4NPC1 | |
| Hydrochloric Acid SCHEMBL27752386 | 0.77 | RAB9A (0.63) | HSD17B10SLC6A7DRD2RAB9ADRD4 | |
| SCHEMBL28396664 | 0.76 | ADRB1 (0.71) | DRD2RAB9ADRD4DRD3ADRB1 | |
| SCHEMBL2628934 | 0.75 | HRH1 (0.57) | SLC6A7DRD2RAB9ADRD4NPC1 | |
| SCHEMBL3147981 | 0.75 | DRD2 (0.43) | HSD17B10SLC6A7DRD2RAB9ADRD4 | |
| SCHEMBL3950684 | 0.74 | ADRA2C (0.45) | HSD17B10SLC6A7DRD2RAB9ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | ABBVIE INC. | 2007-06-21 | — | — | US | claimed |
| US-7196200-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | claimed |
| US-20050159423-A1 | Antibacterial compounds | ABBOTT LABORATORIES | 2005-07-21 | — | — | US | claimed |
| US-7737159-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2010-06-15 | — | — | US | disclosed |
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | ABBVIE INC. | 2007-06-21 | — | — | US | disclosed |
| US-7196200-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | disclosed |
| US-20050159423-A1 | Antibacterial compounds | ABBOTT LABORATORIES | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, FDPS, PGLS | HSD17B10 1808/4885SLC6A7 254/4885DRD2 4721/4885 |
| US-20050159423-A1 | Antibacterial compounds | MRPL21, FDPS, PGLS | HSD17B10 1808/4885SLC6A7 254/4885DRD2 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.