Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 5/20 | 0.36 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069944 | 0.87 | HDAC1 (0.57) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL8079292 | 0.74 | HDAC1 (0.53) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3959226 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4055945 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3959425 | 0.72 | SIRT1 (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC10 | |
| SCHEMBL3951955 | 0.71 | SIRT1 (0.34) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8079294 | 0.71 | HDAC6 (0.49) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL3955607 | 0.69 | SIRT1 (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL4055523 | 0.69 | BCHE (0.56) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5279510 | 0.65 | HDAC3 (0.56) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |