Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | FPR1 | P21462 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079286 | 0.87 | HDAC3 (0.70) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4055523 | 0.82 | BCHE (0.56) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4058179 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5279510 | 0.78 | HDAC3 (0.56) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5483551 | 0.76 | ALDH1A1 (0.66) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5281030 | 0.76 | FPR1 (0.58) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4049526 | 0.75 | ADORA3 (0.38) | HDAC1HDAC6CYP1A2 | |
| SCHEMBL3952192 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5281920 | 0.74 | TAAR1 (0.50) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5363758 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |