Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.60 |
| ▸ | LPL | P06858 | 2/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.54 |
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14842165 | 0.87 | ENPP2 (0.58) | ENPP2LPLLIPGMGLLKDM4E | |
| SCHEMBL16576680 | 0.81 | ENPP2 (0.60) | ENPP2LPLLIPGMGLLKDM4E | |
| SCHEMBL1814455 | 0.79 | ENPP2 (0.58) | ENPP2LPLLIPGMGLLKDM4E | |
| SCHEMBL2230985 | 0.78 | ENPP2 (0.67) | ENPP2LPLLIPGMGLLKDM4E | |
| SCHEMBL14749935 | 0.78 | ENPP2 (0.51) | ENPP2LPLLIPGMGLLKDM4E | |
| SCHEMBL3965528 | 0.78 | ENPP2 (0.51) | ENPP2LPLLIPGMGLLKDM4E | |
| SCHEMBL5872608 | 0.77 | ENPP2 (0.72) | ENPP2LPLLIPGMGLLKDM4E | |
| SCHEMBL8832 | 0.75 | ENPP2 (1.00) | ENPP2LPLLIPGMGLLKDM4E | |
| SCHEMBL3647842 | 0.75 | TAAR1 (0.52) | ALDH1A1 | |
| SCHEMBL3948382 | 0.75 | LPL (0.52) | ENPP2LPLLIPGMGLLCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230371363-A1 | COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-11-16 | — | — | US | disclosed |
| US-20230371363-A1 | COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-11-16 | — | — | US | disclosed |
| US-20220389008-A1 | 4-QUINOLINONE ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | US | disclosed |
| CN-113943238-B | Substituted diphenyl sulfide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-11-01 | — | — | CN | disclosed |
| WO-2022214519-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-10-13 | — | — | WO | disclosed |
| EP-4038067-A1 | 4-QUINOLINONE ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-08-10 | — | — | EP | disclosed |
| CN-114450288-A | 4-quinolinone antibacterial compounds | 爱尔兰詹森科学公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2022069421-A1 | COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-04-07 | — | — | WO | disclosed |
| CN-113943238-A | Substituted diphenyl sulfide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-01-18 | — | — | CN | disclosed |
| EP-2943481-B1 | (HETERO)ARYLACETAMIDE DERIVATIVES AS ANTIRETROVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2018-05-02 | — | — | EP | disclosed |
| EP-2943481-A1 | (HETERO) ARYLACETAMIDE DERIVATIVES AS ANTIRETROVIRAL AGENTS | Gilead Sciences, Inc. (US) | 2015-11-18 | — | — | EP | disclosed |
| US-9050344-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20140221346-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140221347-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| WO-2014110297-A1 | (HETERO) ARYLACETAMIDE DERIVATIVES AS ANTIRETROVIRAL AGENTS | GILEAD SCIENCES, INC. (US) | 2014-07-17 | — | — | WO | disclosed |
| EP-2010487-A1 | 5-AMIDO-2-CARBOXAMIDE INDOLES | F. Hoffmann-Roche AG (CH) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007115938-A1 | 5-AMIDO-2-CARBOXAMIDE INDOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230371363-A1 | COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES | EPCAM, SELE, CTCF | ENPP2 2533/4885LPL 2596/4885LIPG 1823/4885 |
| US-20140221347-A1 | THERAPEUTIC COMPOUNDS | HAVCR2, SARS1, FURIN | ENPP2 3470/4885LPL 1144/4885LIPG 1078/4885 |
| US-20140221346-A1 | THERAPEUTIC COMPOUNDS | HAVCR2, SARS1, G6PD | ENPP2 2810/4885LPL 1208/4885LIPG 1111/4885 |
| US-20220389008-A1 | 4-QUINOLINONE ANTIBACTERIAL COMPOUNDS | NQO2, NDUFS3, QARS1 | ENPP2 1768/4885LPL 4377/4885LIPG 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.