SCHEMBL3953404

SCHEMBL3953404

FC(I)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717178 1.00 LMNA (0.32) LMNA
SCHEMBL11704124 1.00 LMNA (0.32) LMNA
SCHEMBL9717223 0.97
SCHEMBL11705242 0.89
SCHEMBL28018404 0.82 LMNA (0.33) LMNA
SCHEMBL28528173 0.79
SCHEMBL4807078 0.79 LMNA (0.41) LMNA
SCHEMBL6352987 0.79 LMNA (0.41) LMNA
SCHEMBL2527459 0.78
SCHEMBL11803480 0.78 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576245-B2 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof FLUOROUS TECHNOLOGIES INCORPORATED (US) 2009-08-18 US disclosed
US-20060128957-A1 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof FLUOROUS TECHNOLOGIES INCORPORATED 2006-06-15 US disclosed
US-7060850-B2 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof FLUOROUS TECHNOLOGIES INCORPORATED (US) 2006-06-13 US disclosed
US-20040073054-A1 New fluorous tagging and scavenging reactants and methods of synthesis and use thereof FLUOROUS TECHNOLOGIES, INC. 2004-04-15 US disclosed
US-6534684-B1 Compounds resistant to hydrolysis and highly soluble in perfluorinated solvents; transition metal ligands for preparing catalysts used in two-phase catalysis with fluorine-containing phase such as hydroformylation of olefins CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2003-03-18 US disclosed
EP-0655069-A1 AMPHIPHILIC COMPOUNDS DERIVED FROM AMINO ACIDS OR PEPTIDES, THEIR METHODS OF SYNTHESIS AND THEIR APPLICATION AS DRUG DELIVERY SYSTEMS ALLIANCE PHARMACEUTICAL CORP. (US) 1995-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040073054-A1 New fluorous tagging and scavenging reactants and methods of synthesis and use thereof THEM6, NOTUM, RNF31 LMNA 4046/4885
US-20060128957-A1 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof PFAS, CTSF, AFF2 LMNA 4174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.