Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL6815543 | 0.88 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| Hexane SCHEMBL6846620 | 0.88 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| Heptane SCHEMBL1077786 | 0.86 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL866880 | 0.79 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10581578 | 0.79 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28312932 | 0.78 | GPR84 (0.54) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL27878051 | 0.76 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL337541 | 0.76 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8816556 | 0.76 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7295527 | 0.76 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706123-A4 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | HERB LTD D (IL) | 2009-07-15 | — | — | EP | claimed |
| US-20070154572-A1 | Compositions derived from portulaca oleracea l. and methods of using same for modulating blood glucose levels | D-HERB LTD. (IL) | 2007-07-05 | — | — | US | claimed |
| EP-1706123-A2 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | D-Herb Ltd. (IL) | 2006-10-04 | — | — | EP | claimed |
| WO-2005060349-A2 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | D-HERB LTD. (IL) | 2005-07-07 | — | — | WO | claimed |
| EP-3083586-B1 | NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS | Bayer Pharma AG (DE) | 2018-04-18 | — | — | EP | disclosed |
| US-9581601-B2 | Method of detection of amino acid sequence and/or identification of peptides and proteins, by use of a new derivatization reagent and synthesis of 5-formyl-benzene-1,3-disulphonic acid as derivatization reagent | RUDJER BOSKOVIC INSTITUTE (HR) | 2017-02-28 | — | — | US | disclosed |
| EP-3083586-A1 | NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS | Bayer Pharma Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-20150233937-A1 | METHOD OF DETECTION OF AMINO ACID SEQUENCE AND/OR IDENTIFICATION OF PEPTIDES AND PROTEINS, BY USE OF A NEW DERIVATIZATION REAGENT AND SYNTHESIS OF 5-FORMYL-BENZENE-1,3-DISULPHONIC ACID AS DERIVATIZATION REAGENT | RUDJER BOSKOVIC INSTITUTE (HR) | 2015-08-20 | — | — | US | disclosed |
| WO-2015091426-A1 | NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
| EP-1706123-A4 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | HERB LTD D (IL) | 2009-07-15 | — | — | EP | disclosed |
| US-20070154572-A1 | Compositions derived from portulaca oleracea l. and methods of using same for modulating blood glucose levels | D-HERB LTD. (IL) | 2007-07-05 | — | — | US | disclosed |
| EP-1706123-A2 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | D-Herb Ltd. (IL) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005060349-A2 | COMPOSITIONS DERIVED FROM PORTULACA OLERACEA L. AND METHODS OF USING SAME FOR MODULATING BLOOD GLUCOSE LEVELS | D-HERB LTD. (IL) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150233937-A1 | METHOD OF DETECTION OF AMINO ACID SEQUENCE AND/OR IDENTIFICATION OF PEPTIDES AND PROTEINS, BY USE OF A NEW DERIVATIZATION REAGENT AND SYNTHESIS OF 5-FORMYL-BENZENE-1,3-DISULPHONIC ACID AS DERIVATIZATION REAGENT | PTMS, FABP5, FPR1 | GPR84 1941/4885FFAR1 621/4885MAPT 4808/4885 |
| US-20070154572-A1 | Compositions derived from portulaca oleracea l. and methods of using same for modulating blood glucose levels | PNLIP, LIPC, SLC5A1 | GPR84 1988/4885FFAR1 943/4885MAPT 2081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.