Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 4/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956359 | 0.76 | MAPT (0.54) | FBP1MAPTPOLBMEN1KMT2A | |
| SCHEMBL11887661 | 0.76 | MAPT (0.54) | FBP1MAPTPOLBMEN1KMT2A | |
| SCHEMBL28211098 | 0.76 | MAPT (0.57) | FBP1MAPTPOLBMEN1KMT2A | |
| SCHEMBL171243 | 0.75 | RAB9A (0.55) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL6651221 | 0.75 | RAB9A (0.52) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL3956334 | 0.75 | MAPT (0.50) | FBP1MAPTPOLBMEN1KMT2A | |
| SCHEMBL3956332 | 0.75 | MAPT (0.50) | FBP1MAPTPOLBMEN1KMT2A | |
| SCHEMBL3957251 | 0.74 | FBP1 (0.59) | FBP1MAPTPOLBMEN1KMT2A | |
| SCHEMBL12170965 | 0.74 | NPC1 (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7827259 | 0.73 | FBP1 (1.00) | FBP1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970735-A | The salt and crystal form of compound | 诺华公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-106045993-A | Salt and crystal form of compound | 诺华股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-102372711-B | Imidazo quinoline PI3K and mTOR (mammalian target of rapamycin) dual inhibitor | KBP BIOSCIENCES CO LTD | 2014-09-17 | — | — | CN | disclosed |
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | disclosed |
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) | 2004-12-30 | — | — | US | disclosed |
| EP-1386908-A1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | KCNMA1, KCNA5, KCNA1 | FBP1 2146/4885MAPT 2941/4885POLB 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.