Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950074 | 0.91 | ALDH1A1 (0.32) | — | |
| SCHEMBL3957185 | 0.90 | DRD2 (0.35) | DRD2HTR2ADRD3 | |
| SCHEMBL3954323 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL4176367 | 0.80 | DRD2 (0.34) | DRD2HTR2ADRD3 | |
| SCHEMBL3951429 | 0.80 | DRD2 (0.31) | DRD2HTR2ADRD3PIM1 | |
| SCHEMBL4044981 | 0.79 | CHRM2 (0.36) | DRD2HTR2ADRD3PIM1 | |
| SCHEMBL3950039 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL3951433 | 0.78 | CARM1 (0.43) | — | |
| SCHEMBL3948245 | 0.76 | GNAI3 (0.33) | DRD2HTR2ADRD3PIM1NAMPT | |
| SCHEMBL3950698 | 0.76 | ALDH1A1 (0.34) | DRD2HTR2ADRD3NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |