Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 11/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 11/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 11/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.36 |
| ▸ | DRD2 | P14416 | 10/20 | 0.34 |
| ▸ | DRD3 | P35462 | 10/20 | 0.34 |
| ▸ | DRD4 | P21917 | 7/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949679 | 0.94 | CHRM5 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3956154 | 0.93 | CYP1A2 (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3950039 | 0.88 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3957672 | 0.87 | CYP1A2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3950123 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3950698 | 0.82 | ALDH1A1 (0.34) | DRD2DRD3DRD4HTR2AALDH1A1 | |
| SCHEMBL3956741 | 0.82 | ALDH1A1 (0.39) | DRD2DRD3HTR2AALDH1A1 | |
| SCHEMBL4044985 | 0.80 | DRD2 (0.32) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3956360 | 0.79 | DRD2 (0.31) | DRD2DRD3HTR2APIM1 | |
| SCHEMBL3949506 | 0.78 | ALDH1A1 (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |