Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664172 | 0.94 | RAB9A (0.32) | LMNAMAPTL3MBTL1 | |
| SCHEMBL3959108 | 0.94 | RAB9A (0.32) | LMNAMAPTL3MBTL1 | |
| SCHEMBL3953598 | 0.94 | ALK (0.34) | LMNAPOLBNPSR1ALKCYP1A1 | |
| SCHEMBL30750473 | 0.92 | PTGDR2 (0.34) | ALKPTGDR2 | |
| SCHEMBL1815536 | 0.92 | PTGDR2 (0.34) | ALKPTGDR2 | |
| SCHEMBL4188623 | 0.91 | PAX8 (0.31) | L3MBTL1 | |
| SCHEMBL25605282 | 0.91 | TP53 (0.33) | LMNAL3MBTL1 | |
| SCHEMBL3955033 | 0.91 | ALK (0.33) | ALK | |
| SCHEMBL1186910 | 0.89 | ALDH1A1 (0.35) | — | |
| SCHEMBL31337370 | 0.89 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078006-B1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL INC (US) | 2018-11-07 | — | — | EP | claimed |
| EP-2078006-A2 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2009-07-15 | — | — | EP | claimed |
| WO-2008054942-A2 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2008-05-08 | — | — | WO | claimed |
| US-20080103301-A1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2008-05-01 | — | — | US | claimed |
| EP-2078006-B1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL INC (US) | 2018-11-07 | — | — | EP | disclosed |
| US-9006427-B2 | Photochromic materials demonstrating improved fade rates | TRANSITIONS OPTICAL, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-8748634-B2 | Photochromic materials demonstrating improved fade rates | TRANSITIONS OPTICAL, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| US-20140155598-A1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| EP-2078006-A2 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008054942-A2 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20080103301-A1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | TRANSITIONS OPTICAL, INC. (US) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103301-A1 | PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES | PNPO, FLAD1, CRY2 | LMNA 727/4885POLB 838/4885NPSR1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.