Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.66 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944406 | 0.90 | SLC6A3 (0.59) | SIGMAR1 | |
| SCHEMBL8114316 | 0.90 | SLC6A3 (0.59) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10464381 | 0.89 | SLC6A3 (0.58) | SIGMAR1 | |
| SCHEMBL3451685 | 0.83 | DRD2 (0.46) | SIGMAR1GRIN2B | |
| SCHEMBL8099349 | 0.81 | TEAD3 (0.56) | SIGMAR1LTA4H | |
| SCHEMBL6944656 | 0.81 | TEAD3 (0.56) | SIGMAR1LTA4H | |
| SCHEMBL6942105 | 0.81 | NAMPT (0.45) | SIGMAR1GRIN2B | |
| SCHEMBL6550825 | 0.80 | SIGMAR1 (1.00) | SIGMAR1POLBLTA4H | |
| SCHEMBL2962629 | 0.80 | SIGMAR1 (1.00) | SIGMAR1POLBLTA4H | |
| SCHEMBL6947746 | 0.80 | TEAD3 (0.52) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009033689-A1 | PIPERIDONE DERIVATIVES AND MEDICAL USES THEREOF | HEINRICH-PETTE-INSTITUT (DE) | 2009-03-19 | — | — | WO | disclosed |
| EP-2036556-A1 | Piperidone derivatives and medical uses thereof | Heinrich-Pette-Institut (DE) | 2009-03-18 | — | — | EP | disclosed |
| EP-2036556-A1 | Piperidone derivatives and medical uses thereof | Heinrich-Pette-Institut (DE) | 2009-03-18 | — | — | EP | disclosed |