Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818191 | 0.82 | TSHR (0.64) | SIGMAR1OPRM1 | |
| SCHEMBL22904117 | 0.76 | LMNA (0.57) | SIGMAR1OPRM1 | |
| SCHEMBL8092982 | 0.73 | SIGMAR1 (0.85) | SIGMAR1CCR3 | |
| SCHEMBL5612374 | 0.71 | SIGMAR1 (0.70) | SIGMAR1CCR3 | |
| SCHEMBL20676123 | 0.71 | SIGMAR1 (0.84) | SIGMAR1CCR3 | |
| SCHEMBL3251614 | 0.71 | SIGMAR1 (0.90) | SIGMAR1CCR3 | |
| SCHEMBL3397833 | 0.71 | SIGMAR1 (0.67) | SIGMAR1 | |
| SCHEMBL6608842 | 0.71 | CCR5 (0.53) | SIGMAR1 | |
| SCHEMBL7366514 | 0.70 | SIGMAR1 (1.00) | SIGMAR1CCR3 | |
| SCHEMBL28881215 | 0.70 | SIGMAR1 (0.93) | SIGMAR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037168-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-03-26 | — | — | WO | disclosed |