SCHEMBL396017

SCHEMBL396017

Oc1c(C(F)(F)F)cccc1C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.55
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
LMNA P02545 2/20 0.40
GAA P10253 1/20 0.40
PDK2 Q15119 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
AXL P30530 1/20 0.39
NFKB1 P19838 1/20 0.39
KIF11 P52732 1/20 0.39
HSD17B10 Q99714 2/20 0.38
ADAMTS4 O75173 1/20 0.38
EGFR P00533 1/20 0.38
CA1 P00915 1/20 0.38
FYN P06241 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861978 0.88 CA2 (0.77) CA2GABRA1GABRB2ALDH1A1TDP1
SCHEMBL5515511 0.87 ALDH1A1 (0.52) CA2GABRA1GABRB2LMNAGAA
SCHEMBL8007178 0.87 PDK2 (0.44) CA2GABRA1GABRB2LMNAGAA
SCHEMBL20600777 0.85 ALB (0.43) CA2GABRA1GABRB2LMNAGAA
SCHEMBL23324839 0.83 CA2 (0.39) CA2GABRA1GABRB2LMNAGAA
SCHEMBL3177363 0.83 GABRA1 (0.65) CA2GABRA1GABRB2GAAALDH1A1
SCHEMBL1603128 0.83 CA2 (0.39) CA2GABRA1GABRB2LMNAGAA
SCHEMBL9860926 0.83 SMN1; SMN2 (0.42) CA2GABRA1GABRB2LMNAGAA
SCHEMBL103733 0.83 MMP2 (0.42) CA2GABRA1GABRB2LMNAGAA
SCHEMBL5312045 0.83 CA2 (0.39) CA2GABRA1GABRB2LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119953042-A Organic photochromic glass and preparation process thereof 上海匠心玻璃装饰工程有限公司 2025-05-09 CN claimed
CN-118085543-A Copper-clad plate prepreg for high frequency and preparation method thereof 上海华芯晟新材料有限公司 2024-05-28 CN claimed
CN-111363308-B Epoxy modified low-dielectric fluorine-containing polyphenyl ether coating and high-frequency high-speed copper-clad plate prepared from same 顺德职业技术学院 2022-12-23 CN claimed
CN-111471144-B Acrylic acid modified low-dielectric fluorine-containing polyphenyl ether mixed glue and 5G copper-clad plate prepared from same 顺德职业技术学院 2022-05-31 CN claimed
US-20140288249-A1 Methods for Producing Polyolefins With Catalyst Systems UNIVATION TECHNOLOGIES, LLC (US) 2014-09-25 US claimed
EP-2776476-A1 METHODS FOR PRODUCING POLYOLEFINS WITH CATALYST SYSTEMS Univation Technologies, LLC (US) 2014-09-17 EP claimed
CN-103930452-A Process for producing polyolefins using a catalyst system UNIVATION TECH LLC 2014-07-16 CN claimed
WO-2013070602-A1 METHODS FOR PRODUCING POLYOLEFINS WITH CATALYST SYSTEMS UNIVATION TECHNOLOGIES, LLC (US) 2013-05-16 WO claimed
EP-1113026-B1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL CO (JP) 2009-12-09 EP claimed
US-6620823-B2 Antiinflammatory agents; rheumatic disorders BRISTOL-MYERS SQUIBB PHARME COMPANY 2003-09-16 US claimed
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
CN-119953042-A Organic photochromic glass and preparation process thereof 上海匠心玻璃装饰工程有限公司 2025-05-09 CN disclosed
EP-4484407-A2 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2025-01-01 EP disclosed
CN-116082563-B (Meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2024-09-20 CN disclosed
CN-118359760-A Optical resin, optical element, and optical device 株式会社 尼康 2024-07-19 CN disclosed
WO-2000059285-A2 NOVEL LACTAM INHIBITORS OF MATRIX METALLOPROTEINASES, TNF-α, AND AGGRECANASE DU PONT PHARMACEUTICALS COMPANY (US) 2000-10-12 WO disclosed
US-6057336-A ANTIINFLAMMATORY AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-02 US disclosed
EP-0949273-A1 MODIFIED PARTICLES, CARRIER PREPARED THEREFROM, OLEFIN POLYMERIZATION CATALYST COMPONENT PREPARED THEREFROM, OLEFIN POLYMERIZATION CATALYST PREPARED THEREFROM, AND PROCESS FOR PREPARING OLEFIN POLYMER Sumitomo Chemical Company, Limited (JP) 1999-10-13 EP disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product CD38, PARP9, MCCC2 CA2 243/4885GABRA1 285/4885GABRB2 692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.