SCHEMBL396070

SCHEMBL396070

C=C(Cc1cccc(S(=O)(=O)N(C)C)c1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.56
NPC1 O15118 2/20 0.56
TNF P01375 1/20 0.56
NOD1 Q9Y239 1/20 0.56
ALDH1A1 P00352 6/20 0.50
TP53 P04637 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
TSHR P16473 1/20 0.46
LMNA P02545 1/20 0.46
KCNJ6 P48051 1/20 0.46
KCNJ5 P48544 1/20 0.46
KCNJ3 P48549 1/20 0.46
RXFP1 Q9HBX9 2/20 0.46
MAPK1 P28482 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394852 0.86 POLB (0.54) RAB9AALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL18151491 0.85 RAB9A (0.62) RAB9ANPC1TNFNOD1ALDH1A1
SCHEMBL397779 0.82 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2KMT2AMEN1TSHR
SCHEMBL19211731 0.82 RAB9A (0.62) RAB9ANPC1TNFNOD1ALDH1A1
SCHEMBL397249 0.81 CA1 (0.48) ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL398496 0.80 POLB (0.44) SMN1; SMN2LMNAMAPK1L3MBTL1
SCHEMBL392888 0.78 ALDH1A1 (0.45) ALDH1A1KMT2ALMNA
SCHEMBL3423556 0.78 CTBP2 (0.44)
SCHEMBL398535 0.77 KDM4E (0.52) RAB9ANPC1ALDH1A1SMN1; SMN2KMT2A
SCHEMBL19212541 0.77 RAB9A (0.68) RAB9ANPC1TNFNOD1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed