Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.46 |
| ▸ | CCR2 | P41597 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722397 | 0.91 | ALDH1A1 (0.55) | CHRM2CHRM3ALDH1A1ROCK2CCR2 | |
| SCHEMBL14832157 | 0.87 | CHRM2 (0.46) | CHRM2CHRM3PRMT6F10ROCK2 | |
| SCHEMBL14220887 | 0.85 | CHRM2 (0.51) | CHRM2CHRM3KDM4EALDH1A1GAA | |
| SCHEMBL14048044 | 0.84 | F10 (0.49) | CHRM2CHRM3KDM4EALDH1A1GAA | |
| SCHEMBL14618789 | 0.84 | SIGMAR1 (0.61) | L3MBTL1 | |
| SCHEMBL16760957 | 0.84 | SIGMAR1 (0.56) | ALDH1A1PRMT6 | |
| SCHEMBL7761231 | 0.84 | PRMT6 (0.68) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL14625389 | 0.83 | CHRM2 (0.50) | CHRM2CHRM3KDM4EALDH1A1GAA | |
| SCHEMBL10989753 | 0.82 | DRD2 (0.60) | CHRM2CHRM3NPC1RAB9AKDM4E | |
| SCHEMBL21178265 | 0.82 | ALDH1A1 (0.68) | KDM4EALDH1A1POLBPRMT6ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009029998-A1 | RETROMETABOLIC COMPOUNDS | CYTOPIA RESEARCH PTY LTD (AU) | 2009-03-12 | — | — | WO | disclosed |