SCHEMBL3962828

SCHEMBL3962828

Cc1cc2ncn(C)c2cc1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
POLB P06746 1/20 0.52
KDM4E B2RXH2 1/20 0.49
GAA P10253 1/20 0.49
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KCNH2 Q12809 1/20 0.46
CHRNB2 P17787 1/20 0.46
CHRNA4 P43681 1/20 0.46
TP53 P04637 2/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GGPS1 O95749 1/20 0.44
FDPS P14324 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
DYRK1A Q13627 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19764100 1.00 LMNA (0.55) LMNAMEN1KMT2APOLBKDM4E
SCHEMBL10423427 0.88 CHRNB2 (0.50) LMNAMEN1KMT2APOLBKDM4E
SCHEMBL9335217 0.88 LMNA (0.45) LMNAMEN1KMT2APOLBKDM4E
SCHEMBL19267535 0.85 CHRNB2 (0.52) LMNAKMT2AKDM4EGAANPC1
SCHEMBL17563257 0.84 CHRNB2 (0.41) LMNAMEN1KMT2APOLBKDM4E
SCHEMBL12121752 0.84 PRPS1 (0.44) LMNAMEN1KMT2APOLBKDM4E
SCHEMBL30089764 0.84 CHRNB2 (0.41) LMNAMEN1KMT2APOLBKDM4E
SCHEMBL13137241 0.84 CHRNB2 (0.41) LMNAMEN1KMT2APOLBKDM4E
SCHEMBL22704837 0.84 DYRK1A (0.46) LMNAMEN1KMT2APOLBKDM4E
SCHEMBL19915916 0.82 LMNA (0.55) LMNAMEN1KMT2APOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
US-7169948-B2 Anionic and neutral complexes of ruthenium (II) with nitrogen oxide SIGEA S.R.L. (IT) 2007-01-30 US claimed
EP-1392707-B1 NEW ANIONIC AND NEUTRAL COMPLEXES OF RUTHENIUM (II) WITH NITROGEN OXIDE SIGEA SRL (IT) 2005-11-09 EP claimed
US-20040106799-A1 Anionic and neutral complexes of ruthenium (II) with nitrogen oxide SIGEA S.R.L. (IT) 2004-06-03 US claimed
EP-1228077-B1 RUTHENIUM (II) COMPLEXES WITH HIGH ANTITUMORAL AND ANTIMETASTATIC ACTIVITIES SIGEA SRL (IT) 2003-06-11 EP claimed
EP-0915895-B1 NEW SALTS OF ANIONIC COMPLEXES OF RU(III), AS ANTIMETASTATIC AND ANTINEOPLASTIC AGENTS SIGEA SRL (IT) 2003-05-21 EP claimed
US-6221905-B1 ANTICANCER AGENTS SIGEA S.R.L. (IT) 2001-04-24 US claimed
CN-115974788-B Method for synthesizing alpha-straight-chain alkyl substituted heteroarene 苏州大学 2025-06-17 CN disclosed
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-05-30 US disclosed
WO-2024077391-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF UNIVERSITE DE MONTREAL (CA) 2024-04-18 WO disclosed
EP-4347544-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES Dow Technology Investments LLC (US) 2024-04-10 EP disclosed
WO-2024026596-A1 METHOD FOR SYNTHESIZING α-LINEAR ALKYL SUBSTITUTED HETEROARENE 苏州大学 2024-02-08 WO disclosed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
EP-0709375-A2 Therapeutic heterocycles ZENECA LIMITED (GB) 1996-05-01 EP disclosed
US-5015473-A Beta-lactamase inhibitors PFIZER INC. (US) 1991-05-14 US disclosed
US-4898872-A Imidazo[4,5-b]pyridyl quinolone cardiac stimulants PFIZER INC. (US) 1990-02-06 US disclosed
US-4826833-A ANTIBIOTICS PFIZER INC. (US) 1989-05-02 US disclosed
EP-0290153-A1 Heterobicyclic quinolone derivatives Pfizer Limited (GB) 1988-11-09 EP disclosed
US-4595701-A Reacting carbon monoxide and hydrogen in liquid phase in the presence of a rhodium and trialkylphosphine catalyst AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1986-06-17 US disclosed
US-4460709-A Process for producing oxygen-containing organic compounds AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1984-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES ADH1C, ADH5, ALDH2 LMNA 1542/4885MEN1 4692/4885KMT2A 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.