SCHEMBL229518

SCHEMBL229518

C=C(C)C(=O)OCC(C)(C)O[SiH3]

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.41
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10937523 0.82 TSHR (0.45) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL17300333 0.82 TSHR (0.45) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL81164 0.81 THRB (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2229572 0.79 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL2414620 0.79 ALDH1A1 (0.40) TSHRALDH1A1
SCHEMBL15337 0.79 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL396824 0.79 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL51592 0.79 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1803423 0.78 TSHR (0.42) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL9241171 0.78 TSHR (0.42) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
CN-107743492-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-07-17 CN claimed
EP-3006599-B1 METHOD FOR COATING THE SURFACE OF A METAL SUBSTRATE SAFRAN LANDING SYSTEMS (FR) 2019-03-27 EP claimed
US-10066301-B2 Method of coating the surface of a metal substrate MESSIER-BUGATTI-DOWTY (FR) 2018-09-04 US claimed
US-20160102406-A1 METHOD OF COATING THE SURFACE OF A METAL SUBSTRATE MESSIER-BUGATTI-DOWTY (FR) 2016-04-14 US claimed
EP-3006599-A1 METHOD FOR COATING THE SURFACE OF A METAL SUBSTRATE Messier-Bugatti-Dowty (FR) 2016-04-13 EP claimed
EP-2024406-B1 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING (US) 2012-08-01 EP claimed
US-8124689-B2 Silicone acrylate hybride composition and method of making same DOW CORNING CORPORATION (US) 2012-02-28 US claimed
US-20090196911-A1 Silicone Acrylate Hybride Composition and Method Of Making Same DOW SILICONES CORPORATION 2009-08-06 US claimed
EP-2024406-A2 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING CORPORATION (US) 2009-02-18 EP claimed
WO-2007145996-A9 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING (US) 2008-02-14 WO claimed
WO-2007145996-A2 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING CORPORATION (US) 2007-12-21 WO claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
EP-4395749-B1 TRANSDERMAL THERAPEUTIC SYSTEM FOR THE TRANSDERMAL ADMINISTRATION OF GUANFACINE COMPRISING GUANFACINE AND A MONO-CARBOXYLIC ACID LTS LOHMANN THERAPIE SYSTEME AG (DE) 2025-11-19 EP disclosed
EP-3996692-B1 TRANSDERMAL THERAPEUTIC SYSTEM COMPRISING AN ACTIVE AGENT-CONTAINING LAYER COMPRISING A SILICONE-CONTAINING POLYMER AND A SKIN CONTACT LAYER COMPRISING A SILICONE GEL ADHESIVE LTS LOHMANN THERAPIE SYSTEME AG (DE) 2025-06-11 EP disclosed
US-12240868-B2 Organic silicon compound and production method therefor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-03-04 US disclosed
EP-0486279-B2 Process for removing acidic impurities from alkoxysilanes SHINETSU CHEMICAL CO (JP) 1999-12-01 EP disclosed
US-5247117-A Neutralization with sterically hindered alcohols or amines, distillation SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-09-21 US disclosed
EP-0486279-A1 Process for removing acidic impurities from alkoxysilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885THRB 4533/4885ALDH1A1 402/4885
US-20090196911-A1 Silicone Acrylate Hybride Composition and Method Of Making Same MMS19, CAD, ACR TSHR 4760/4885THRB 4098/4885ALDH1A1 2679/4885
US-12240868-B2 Organic silicon compound and production method therefor OR51E2, MSL1, SOS1 TSHR 4456/4885THRB 3708/4885ALDH1A1 2353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.