Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153138 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL4153141 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL1799678 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL4148373 | 0.72 | NOTUM (0.59) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL12091036 | 0.72 | FAAH (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL27752608 | 0.72 | RAB9A (0.41) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL4142795 | 0.72 | FAAH (0.40) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL7021994 | 0.71 | ALOX15 (0.59) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL13744593 | 0.69 | FAAH (0.44) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL13484386 | 0.68 | FAAH (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079734-A1 | OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NeuroSearch A/S (DK) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008049864-A1 | OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2008-05-02 | — | — | WO | disclosed |