Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.35 |
| ▸ | THRB | P10828 | 6/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226109 | 0.90 | NPSR1 (0.34) | RORCTHRB | |
| SCHEMBL3227188 | 0.86 | THRB (0.46) | RORCTHRBTHRA | |
| SCHEMBL3226718 | 0.84 | THRB (0.37) | RORCTHRBTHRA | |
| SCHEMBL3962431 | 0.84 | THRA (0.39) | THRBTHRA | |
| SCHEMBL3226111 | 0.80 | THRB (0.43) | RORCTHRBTHRA | |
| SCHEMBL3233002 | 0.80 | RORC (0.55) | RORCTHRBTHRA | |
| SCHEMBL3219376 | 0.78 | ALDH1A1 (0.38) | RORCTHRBTHRA | |
| SCHEMBL3713161 | 0.78 | THRB (0.43) | RORCTHRBTHRA | |
| SCHEMBL3224530 | 0.77 | POLB (0.45) | RORCTHRB | |
| SCHEMBL3227224 | 0.77 | THRA (0.47) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079678-A2 | SELECTIVE TR-BETA 1 AGONIST | Cadila Healthcare Limited (IN) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008062469-A2 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |