Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833419 | 0.83 | ESR1 (0.46) | ESR1ACP3GLSCXCL8ALDH1A1 | |
| SCHEMBL15695548 | 0.81 | ESR1 (0.45) | ESR1ACP3GLSCXCL8ALDH1A1 | |
| SCHEMBL30717242 | 0.81 | PTGS2 (0.48) | ESR1ACP3GLSCXCL8ALDH1A1 | |
| SCHEMBL7723973 | 0.81 | ESR1 (0.45) | ESR1ACP3ALDH1A1NPC1RAB9A | |
| SCHEMBL15641407 | 0.81 | PTGS2 (0.48) | ESR1ACP3GLSCXCL8ALDH1A1 | |
| SCHEMBL362699 | 0.81 | PTGS2 (0.48) | ESR1ACP3GLSCXCL8ALDH1A1 | |
| SCHEMBL3888924 | 0.79 | ALDH1A1 (0.44) | ESR1ACP3ALDH1A1NPC1RAB9A | |
| SCHEMBL29107358 | 0.79 | CXCL8 (0.46) | ACP3GLSCXCL8ALDH1A1 | |
| SCHEMBL8820174 | 0.79 | ESR1 (0.43) | ESR1ACP3GLSCXCL8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9402250 | 0.79 | PTGS2 (0.47) | ESR1ACP3GLSCXCL8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431510-A | Organic compounds | GIVAUDAN SA | 2016-03-23 | — | — | CN | disclosed |
| CN-102803269-B | Thieno [2,3-B ] pyrimidinedione activators of AMPK and therapeutic uses thereof | POXEL (FR) | 2016-01-13 | — | — | CN | disclosed |
| CN-102803269-A | Thieno [2,3-B ] pyrimidinedione activators of AMPK and therapeutic uses thereof | POXEL | 2012-11-28 | — | — | CN | disclosed |
| US-20090304589-A1 | RADIATION SENSITIVE LIPOSOMES | VARIAN MEDICAL SYSTEMS,INC. (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2009042839-A1 | RADIATION SENSITIVE LIPOSOMES | VARIAN MEDICAL SYSTEMS, INC. (US) | 2009-04-02 | — | — | WO | disclosed |
| US-20070105862-A1 | Heat-shock protein binders | ABBOTT LABORATORIES | 2007-05-10 | — | — | US | disclosed |
| CN-1041596-A | The preparation of stable oxapenem-3-hydroxy acid and as the application of beta-lactamase inhibitor | BAYER AG (DE) | 1990-04-25 | — | — | CN | disclosed |
| CN-1007248-B | PROCESS FOR MANUFACTURING OF FLOOD SUGAR REDUCING MEDICINE-THIAZOLIDINEDIONS | PFIZER (US) | 1990-03-21 | — | — | CN | disclosed |
| CN-1031533-A | Stable 1-Oxapenem-3-carboxylic acid | BAYER AG (DE) | 1989-03-08 | — | — | CN | disclosed |
| CN-86104075-A | Preparation method of hypoglycemic agent-thiazolidinedione | — | 1987-03-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090304589-A1 | RADIATION SENSITIVE LIPOSOMES | PCTP, PLTP, CETP | ESR1 1654/4885ACP3 1581/4885GLS 1026/4885 |
| US-20070105862-A1 | Heat-shock protein binders | HSP90AB1, HSP90AB2P, HSP90B1 | ESR1 3488/4885ACP3 961/4885GLS 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.