Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 8/20 | 0.42 |
| ▸ | NOS1 | P29475 | 7/20 | 0.42 |
| ▸ | NOS3 | P29474 | 4/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378689 | 0.82 | NOS2 (0.59) | ADORA1ADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL9406926 | 0.81 | ADORA1 (0.43) | ADORA1ADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL9406899 | 0.78 | ADORA1 (0.42) | ADORA1ADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL20197285 | 0.77 | GSK3A (0.42) | ADORA1ADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL3650837 | 0.75 | KDM4E (0.45) | ADORA1ADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL8561715 | 0.74 | ADORA1 (0.41) | ADORA1ADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL9041424 | 0.73 | NOS1 (0.56) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9648738 | 0.72 | PI4KA (0.57) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9406720 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBNOS2 | |
| SCHEMBL4052252 | 0.70 | KDM4C (0.41) | ADORA1ADORA3ADORA2API4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034411-A1 | PERHARIDINES AS CDK INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-03-19 | — | — | WO | disclosed |