Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606723 | 0.84 | CYP1A2 (0.34) | HTTCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL3964031 | 0.84 | CYP1A2 (0.34) | HTTCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6547658 | 0.82 | PPARA (0.48) | HTTPPARAPPARGPPARDLMNA | |
| SCHEMBL8894826 | 0.81 | PLA2G4B (0.46) | HTTL3MBTL1 | |
| SCHEMBL8022439 | 0.80 | PPARA (0.51) | HTTPPARAPPARGPPARDLMNA | |
| SCHEMBL6547877 | 0.80 | L3MBTL1 (0.51) | HTTLMNAMAPTL3MBTL1GAA | |
| SCHEMBL5690281 | 0.79 | HTT (0.47) | HTTMAPTL3MBTL1GAA | |
| SCHEMBL8894549 | 0.79 | TP53 (0.47) | HTTL3MBTL1 | |
| SCHEMBL6549825 | 0.78 | HTT (0.43) | HTTCYP1A2CYP2C19MAPTL3MBTL1 | |
| SCHEMBL8660004 | 0.78 | MAPT (0.51) | HTTLMNAMAPTL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298898-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-7569727-B2 | N-{(4-{3-[2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propoxy}-phenyl)-[(E)-ethoxyimino]-methyl}-2,2,2-trifluoroacetamide; exhibit valuable preventive and/or curative activity even at low rates of concentration, while being well tolerated by warm-blooded animals, fish and plants | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| EP-2080752-A1 | Pesticidally active ketone and oxime derivatives | Syngenta Participations AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| US-20080200525-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-20060128670-A1 | Pesticidally active ketone and oxime derivatives | SYNGENTA CROP PROTECTION, INC. | 2006-06-15 | — | — | US | disclosed |
| EP-1638924-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | Syngenta Participations AG (CH) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113273-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298898-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | CHRM2, FOXO3, CHRM1 | HTT 3825/4885HDAC6 1097/4885CYP1A2 252/4885 |
| US-20060128670-A1 | Pesticidally active ketone and oxime derivatives | CHRM2, CHRM1, DDT | HTT 3632/4885HDAC6 1483/4885CYP1A2 124/4885 |
| US-20080200525-A1 | PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES | CHRM2, FOXO3, CHRM1 | HTT 3825/4885HDAC6 1097/4885CYP1A2 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.