SCHEMBL3966237

SCHEMBL3966237

CCCCCC(COc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.49
PPARG P37231 3/20 0.49
PTGES O14684 2/20 0.49
PPARA Q07869 1/20 0.49
TDP1 Q9NUW8 1/20 0.47
LTA4H P09960 2/20 0.46
LMNA P02545 1/20 0.46
PLA2G4B P0C869 1/20 0.46
CNR2 P34972 1/20 0.46
MTNR1A P48039 3/20 0.45
MTNR1B P49286 3/20 0.45
GRIK1 P39086 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
GRIK2 Q13002 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP12 P39900 1/20 0.45
CTRC Q99895 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4550642 0.95 ALOX5 (0.53) ALOX5PPARGPTGESPPARATDP1
SCHEMBL5819286 0.88 PLA2G4B (0.47) TDP1PLA2G4BMTNR1AMTNR1BMMP2
SCHEMBL15514507 0.85 ALOX5 (0.53) ALOX5PPARGPTGESPPARATDP1
SCHEMBL5508346 0.84 TBXA2R (0.49) PPARGPPARALMNAMTNR1AMTNR1B
SCHEMBL5514903 0.83 TBXA2R (0.47) PPARGPPARALMNAMTNR1AMTNR1B
SCHEMBL11052073 0.82 LMNA (0.53) PPARGPPARATDP1LMNAMTNR1A
2-Ethylhexanoic Acid SCHEMBL3847865 0.81 LMNA (0.59) ALOX5PPARGPTGESPPARATDP1
Ethane SCHEMBL5531789 0.81 LMNA (0.49) PPARGPPARATDP1LMNAMTNR1A
SCHEMBL21896387 0.80 KDM4E (0.49) ALOX5PPARGPTGES
SCHEMBL21896388 0.80 KDM4E (0.49) ALOX5PPARGPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020039366-A1 HERBICIDAL COMBINATION UPL LTD (IN) 2020-02-27 WO claimed
EP-1585392-B1 HERBICIDES INHIBITING THE ACTION OF PLANT ACETYL-COA CARBOXYLASE FOR USE AS PESTICIDES. YISSUM RES DEV CO (IL) 2009-03-18 EP claimed
US-20060039943-A1 Acetyl-CoA carboxylase inhibitors for use as pesticides Yissum Research Development Company fo the Hebrew University (IL) 2006-02-23 US claimed
EP-1585392-A2 HERBICIDES INHIBITING THE ACTION OF PLANT ACETYL-COA CARBOXYLASE FOR USE AS PESTICIDES. YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2005-10-19 EP claimed
WO-2004060058-A2 HERBICIDES INHIBITING THE ACTION OF PLANT ACETYL-COA CARBOXYLASE FOR USE AS PESTICIDES. YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2004-07-22 WO claimed
EP-0756632-A1 PLANT GENE SPECIFYING ACETYL COENZYME A CARBOXYLASE AND TRANSFORMED PLANTS CONTAINING SAME ZENECA LIMITED (GB) 1997-02-05 EP claimed
WO-1995029246-A1 PLANT GENE SPECIFYING ACETYL COENZYME A CARBOXYLASE AND TRANSFORMED PLANTS CONTAINING SAME ZENECA LIMITED (GB) 1995-11-02 WO claimed
WO-1994023027-A2 PLANT GENE SPECIFYING ACETYL COENZYME A CARBOXYLASE AND TRANSFORMED PLANTS CONTAINING SAME ZENECA LIMITED (GB) 1994-10-13 WO claimed
CN-114845550-A Superabsorbent polymer and pesticide UPL有限公司 2022-08-02 CN disclosed
US-11083717-B2 Compositions and methods for drug sensitization of parasites THE TEXAS A&M UNIVERSITY SYSTEM (US) 2021-08-10 US disclosed
EP-3659597-A2 COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES The Texas A&M University System (US) 2020-06-03 EP disclosed
US-20200138796-A1 COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES THE TEXAS A&M UNIVERSITY SYSTEM 2020-05-07 US disclosed
WO-2020039366-A1 HERBICIDAL COMBINATION UPL LTD (IN) 2020-02-27 WO disclosed
US-10543200-B2 Compositions and methods for drug sensitization of parasites THE TEXAS A&M UNIVERSITY SYSTEM (US) 2020-01-28 US disclosed
WO-2002022706-A1 LIQUID CRYSTALLINE THERMOSETS FROM ESTER, ESTER-IMIDE, AND ESTER-AMIDE OLIGOMERS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (NASA) (US) 2002-03-21 WO disclosed
US-6308458-B1 APPLYING A PROTOPORPHYRINOGEN OXIDASE (PROTOX)-INHIBITING HERBICIDE TO A TRANSGENIC PLANT OR SEED HAVING A DNA ENCODING A MODIFIED ENZYME HAVNG PROTOX ACTIVITY WHERE THERE IS ONE AMINO ACID REPLACED RELATIVE TO THE WILD-TYE ENZYME NOVARTIS FINANCE CORPORATION 2001-10-30 US disclosed
WO-2001068826-A2 PROTOPORPHYRINOGEN OXIDASE ('PROTOX') GENES SYNGENTA PARTICIPATIONS AG (CH) 2001-09-20 WO disclosed
US-20010016956-A1 Herbicide-tolerant protox genes produced by DNA shuffling WARD ERIC R (US) 2001-08-23 US disclosed
WO-2001012825-A1 HERBICIDE-TOLERANT PROTOPORPHYRINOGEN OXIDASE SYNGENTA PARTICIPATIONS AG (CH) 2001-02-22 WO disclosed
US-6084155-A DNA WHICH CODES FOR A MODIFIED ENZYME WITH AT LEAST ONE AMINO ACID SUBSTITUTION; FOR TRANSFORMING PLANTS NOVARTIS AG (CH) 2000-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200138796-A1 COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES ABCC1, SLC11A2, ABCG2 ALOX5 966/4885PPARG 2475/4885PTGES 1375/4885
US-10543200-B2 Compositions and methods for drug sensitization of parasites ABCC1, SLC11A2, ABCG2 ALOX5 966/4885PPARG 2475/4885PTGES 1375/4885
US-11083717-B2 Compositions and methods for drug sensitization of parasites ABCC1, SLC11A2, ABCG2 ALOX5 966/4885PPARG 2475/4885PTGES 1375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.