Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 6/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361086 | 0.88 | TDP1 (0.55) | PLA2G4BFAAHTDP1TP53TSHR | |
| SCHEMBL3966237 | 0.88 | ALOX5 (0.49) | PLA2G4BMTNR1AMTNR1BMMP2MMP9 | |
| SCHEMBL4550642 | 0.83 | ALOX5 (0.53) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL26456912 | 0.81 | PLA2G4B (0.55) | PLA2G4BMMP2MMP9MMP12PRSS1 | |
| SCHEMBL13431025 | 0.80 | ALDH1A1 (0.48) | PLA2G4BMTNR1AMTNR1BMMP2MMP9 | |
| SCHEMBL15514507 | 0.79 | ALOX5 (0.53) | PLA2G4BFAAHTDP1TP53TSHR | |
| SCHEMBL6231558 | 0.78 | PLA2G4B (0.55) | PLA2G4BTSHR | |
| SCHEMBL9797717 | 0.78 | PLA2G4B (0.55) | PLA2G4BTSHR | |
| SCHEMBL9797915 | 0.78 | PLA2G4B (0.55) | PLA2G4BTSHR | |
| SCHEMBL10451366 | 0.78 | LTA4H (0.49) | PLA2G4BFAAHPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006090072-A1 | PPAR ACTIVATOR DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | NEGMA-LERADS (FR) | 2006-08-31 | — | — | WO | disclosed |