Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119165 | 0.85 | NPC1 (0.60) | NPC1RAB9ARECQLALDH1A1KDM4E | |
| SCHEMBL620542 | 0.85 | LMNA (0.48) | NPC1RAB9ARECQLALDH1A1KDM4E | |
| SCHEMBL9187561 | 0.81 | NPC1 (1.00) | NPC1RAB9ARECQLALDH1A1KDM4E | |
| SCHEMBL9642715 | 0.79 | NPC1 (0.89) | NPC1RAB9ARECQLALDH1A1KDM4E | |
| SCHEMBL619300 | 0.79 | RAB9A (0.48) | NPC1RAB9ARECQLALDH1A1KDM4E | |
| SCHEMBL11292192 | 0.78 | NPC1 (0.74) | NPC1RAB9ARECQLALDH1A1KDM4E | |
| SCHEMBL6793846 | 0.77 | KMT2A (0.62) | NPC1RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL10597265 | 0.76 | MEN1 (0.51) | NPC1RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL10113297 | 0.76 | NPC1 (0.77) | NPC1RAB9ARECQLALDH1A1KDM4E | |
| SCHEMBL6500018 | 0.76 | POLB (0.58) | NPC1RAB9AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517367-B2 | Cationic naphthyldiazo dyes and keratin fibers-coloring agents containing these dyes | WELLA AG (DE) | 2009-04-14 | — | — | US | disclosed |
| US-20080167453-A1 | Cationic Naphthyldiazo Dyes and Keratin Fibers-Coloring Agents Containing These Dyes | WELLA AG (DE) | 2008-07-10 | — | — | US | disclosed |
| EP-1740657-B1 | CATIONIC NAPHTHYLDIAZO DYES AND AGENTS CONTAINING SAID DYES USED TO COLOUR KERATIN FIBRES | WELLA AG (DE) | 2007-09-12 | — | — | EP | disclosed |
| EP-1740657-A1 | CATIONIC NAPHTHYLDIAZO DYES AND AGENTS CONTAINING SAID DYES USED TO COLOUR KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005085362-A1 | CATIONIC NAPHTHYLDIAZO DYES AND AGENTS CONTAINING SAID DYES USED TO COLOUR KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2005-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167453-A1 | Cationic Naphthyldiazo Dyes and Keratin Fibers-Coloring Agents Containing These Dyes | KRT18, KPNB1, KPNA3 | NPC1 1787/4885RAB9A 2730/4885RECQL 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.