Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | GAA | P10253 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 9/20 | 1.00 |
| ▸ | RAB9A | P51151 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | HPGD | P15428 | 8/20 | 1.00 |
| ▸ | GLA | P06280 | 4/20 | 1.00 |
| ▸ | GFER | P55789 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.83 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.83 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.83 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.83 |
| ▸ | POLB | P06746 | 6/20 | 0.81 |
| ▸ | BLM | P54132 | 4/20 | 0.81 |
| ▸ | USP2 | O75604 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9717840 | 0.98 | MAPT (0.97) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL2251258 | 0.91 | MEN1 (1.00) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL12351220 | 0.90 | MEN1 (1.00) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL363703 | 0.89 | MEN1 (1.00) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL20982512 | 0.89 | MEN1 (0.96) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL9767339 | 0.88 | MEN1 (0.90) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL29377327 | 0.88 | MEN1 (0.90) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL28548462 | 0.87 | MEN1 (0.82) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL13221240 | 0.87 | GAA (0.77) | MAPTGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL28615657 | 0.87 | ALDH1A1 (0.87) | MAPTGAAALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772403-A | Preparation method of cross-linked high-temperature-resistant polyimide material | 山东海化集团有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-115678010-B | Polyamide acid, polyimide resin and preparation method thereof | 中国科学院过程工程研究所 | 2023-04-14 | — | — | CN | claimed |
| CN-115678010-A | Polyamide acid, polyimide resin and preparation method thereof | 中国科学院过程工程研究所 | 2023-02-03 | — | — | CN | claimed |
| EP-4716720-A1 | COMPOUND FOR USE AS ANTI-AGING AGENT IN RUBBER BLENDS, AND VEHICLE TIRE | Continental Reifen Deutschland GmbH (DE) | 2026-04-01 | — | — | EP | disclosed |
| WO-2024240313-A1 | COMPOUND FOR USE AS ANTI-AGING AGENT IN RUBBER BLENDS, AND VEHICLE TIRE | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2024-11-28 | — | — | WO | disclosed |
| CN-118772403-A | Preparation method of cross-linked high-temperature-resistant polyimide material | 山东海化集团有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-113736082-B | Polyimide resin for negative photoresist and negative photoresist comprising the same | 上海极紫科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-115678010-B | Polyamide acid, polyimide resin and preparation method thereof | 中国科学院过程工程研究所 | 2023-04-14 | — | — | CN | disclosed |
| CN-115678010-A | Polyamide acid, polyimide resin and preparation method thereof | 中国科学院过程工程研究所 | 2023-02-03 | — | — | CN | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-03-20 | — | — | US | disclosed |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | VERTEX PHARMACEUTICALS INCORPORATED | 2006-04-06 | — | — | US | disclosed |
| US-20050197331-A1 | Novel anti-inflammatory and analgesic heterocyclic amidines that inhibit nitrogen oxide (NO) production | ROTTAPHARM SPA | 2005-09-08 | — | — | US | disclosed |
| EP-1571142-A1 | Novel anti-inflammatory and analgesic heterocyclic amidines that inhibit nitrogen oxide (NO) production | Rottapharm S.p.A. (IT) | 2005-09-07 | — | — | EP | disclosed |
| EP-0843671-A1 | HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997003069-A1 | HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1997-01-30 | — | — | WO | disclosed |
| US-4716168-A | STIMULANTS OF IMMUNE RESPONSE | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0187705-A2 | Imidazo(4,5-f)quinolines useful as immunomodulating agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1986-07-16 | — | — | EP | disclosed |
| US-3947434-A | 9-(P-phenylazoanilino)-7-methyl-1H-imidazo[4,5-f]quinolines | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197331-A1 | Novel anti-inflammatory and analgesic heterocyclic amidines that inhibit nitrogen oxide (NO) production | NOS3, NOS1, NOS2 | MAPT 4542/4885GAA 4310/4885ALDH1A1 1195/4885 |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | MAPT 4269/4885GAA 454/4885ALDH1A1 2165/4885 |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | CFTR, ABCB1, ABCC1 | MAPT 4775/4885GAA 733/4885ALDH1A1 2651/4885 |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | CFTR, ABCC4, ABCC2 | MAPT 4847/4885GAA 650/4885ALDH1A1 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.